Inter-Alpha Inhibitor Proteins are:
IAIP are proteins found in the blood of all mammals and play a critical and essential role in managing and preventing the adverse effects of inflammation. IAIP are essential to health and act as endogenous defenders against severe inflammation.
ProThera has demonstrated the promise of IAIP for the treatment of inflammatory disease in many animal models and has shown that IAIP blood levels correlate closely with the degree of severity of inflammatory disease in humans.
We expect to introduce IAIP as a replacement therapy in critical disease states where IAIP levels decrease as a result of the underlying disease process. IAIP replacement therapy will function as an adjunct to current therapy to:
Applications for IAIP include a host of severe, acute inflammatory diseases including those resulting from infection, injury or trauma. ProThera is targeting high unmet medical needs where there are no treatments for the inflammatory process.